Carrier

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Статья от экспертов

LIPOSOMES AS CARRIER FOR ECHINOCHROME

Sea urchin pigment echinochrome (6-ethyl-2,3,5,7,8-pentahydroxy-1,4-naphthoquinone) (Ech) is a natural bioactive compound with many health-promoting benefits. However, its poor water solubility and bioavailability has limited biomedical application. The inclusion of Ech in complexes with kappacarrageenan (CRG) decreased its oxidative degradation and improved its solubility. In the present study, we used CRG as matrixes for Ech and encapsulated Ech/CRG in into liposomes. Ech did not oxidize and retain stability after the encapsulation in liposomes. According of obtained dates the entrapment efficiency of the Ech in the liposome was 46 %. The lyophilization process did not violate the native form of Ech. The size distribution and ζ-potential of the developed liposomes with and without Ech were determined.

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Статья от экспертов

Charge carrier transport in phenylated poly(naphthoylenebenzimidazole)