А Ля Карт
вид обслуживания, предусматривающий свободный выбор клиентом порционных блюд из предлагаемого ресторанного меню.
оплата за 0,5 суток (дневная, после расчетного часа).
Docetaxel is the most effective chemical agent used in the treatment of hormone-resistant prostate cancer (HRPC). Three different docetaxel-based combinations were tested. The study included 30 patients with HRPC: 10 patients received chemotherapy as intravenous docetaxel, 75 mg/m2 once every 21 days with prednisolone, 10 mg/day (DP); other 10 patients had docetaxel, 75 mg/m2, estramustin, 300 mg/m2 daily, and prednisolone, 10 mg daily (DEP); 10 more patients received a combination of doxorubicin, 20 mg/m2 on day 1 of weeks 1, 3, and 5, ketoconazole, 1200 mg/day on days 1-7 of weeks 1, 3, and 5, docetaxel, 20 mg/m2 on day 1 of weeks 2, 4, and 6, estramustin, 420 mg/day on days 1-7 of weeks 2, 4, and 6, prednisolone, 10 mg daily (DEKP). The study revealed that all these three combinations have about the same efficacy; with their use, the clinical improvement rate was 70-0%. Thus, the use of docetaxel in different combinations is an effective treatment for HRPC
Objective: to evaluate the pharmacodynamic equivalence of 3-month and 28-day formulations of tryptoreline, a sustained-release luteining hormone (LH)-releasing hormone analogue. Subjects and methods. The patients who had a verified diagnosis of locally advanced or metastatic prostate cancer were randomized into groups to have either one injection of a 3-month dosage form (n = 63) or 3 injections of a 28-day formulation at 28-day intervals (n = 68). The onset rate of drug-induced castration, which was defined as a percentage of the patients achieving a plasma testosterone level of ≤0.5 ng/ml, was compared on day 84 (i.e. thrice every 28 days). The plasma profiles of testosterone, LH, and tryptoreline, as well as the changes in the plasma concentration of prostate-specific antigen (PCA) from the baseline values were estimated within 3 months (from the initiation of therapy to day 91). Results. In the 3-month and 28-day groups, the onset rate of drug-induced castration was 98 and 96%, ...
вид обслуживания, предусматривающий свободный выбор клиентом порционных блюд из предлагаемого ресторанного меню.
количество календарных дней до даты заезда, при соблюдении которых аннуляции считаются своевременными.
атмосфера внутри организации, отношение сотрудников к своей работе, руководителям и проводимой ими политике.